Oncodiagnosis Panel : 2002 Adult Central Nervous System Neoplasms 1 Paul

Introduction An estimated 17,000 new cases of primary central nervous system (CNS) tumors will be diagnosed in the United States in 2002 (1). The number of related deaths is projected to be 13,100. These numbers represent a small proportion of the total number of new cancer cases and cancer deaths; however, because of the diversity and complexity of CNS tumors, a multidisciplinary approach is required for their diagnosis and treatment. Treatment options for the different tumors vary widely from observation to aggressive combinations of surgery, radiation therapy, and chemotherapy. Because of the complexity of as well as the controversy surrounding management issues, adult CNS neoplasms were the featured topic of the Oncodiagnosis Panel at the 2002 scientific assembly of the Radiological Society of North America. Experts on neuro-oncology (T.F.C.), neuro–radiation oncology (G.S.B.), diagnostic neuroradiology (J.T.W.), and neurosurgery (M.W.M.) were presented adult CNS neoplasm cases for discussion. The ensuing article outlines each case as presented in the Oncodiagnosis Panel followed by questions posed to the experts and their commentaries given in response. The CNS neoplasms discussed include oligodendroglioma, multiple brain metastases from non-small cell lung cancer, glioblastoma multiforme, and meningioma of the optic nerve.